Graying of the HIV epidemic: a challenge for inpatient medicine providers

Graying of the HIV epidemic: a challenge for inpatient medicine providers
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DOI:
10.3402/jchimp.v5.29428
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发表时间:
2015-01-01
影响因子:
1
通讯作者:
Kisuule, Flora
Kisuule, Flora
中科院分区:
其他
文献类型:
--
作者:
Harris, Che Matthew;McKenzie, Robin;Kisuule, Flora

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自从抗逆转录病毒疗法问世以来,艾滋病毒感染者的寿命延长,到2015年,一半以上的艾滋病毒感染者将超过50岁。此外,随着人口老龄化的持续增长,更多的老年人将成为新的艾滋病毒感染者。与年轻的艾滋病毒感染者和未感染艾滋病毒的患者相比,老年艾滋病毒感染者的首次住院和再住院人数较多,住院时间较长,死亡风险较高。在HIV阳性患者治疗和停止治疗时,与HIV相关的合并症可能会被夸大。此外,艾滋病毒和艾滋病的体征和症状可能与老年人正常衰老过程中的特征相似。预计在住院环境中照顾病人的内科医生将照顾和诊断越来越多的老年艾滋病毒感染者。这对于提高患者护理质量、降低发病率和死亡率以及在疾病病程早期管理新诊断患者同时减少病毒传播至关重要。内科医生应该是在住院普通内科病房开展有针对性和非有针对性的艾滋病毒筛查工作的核心领导者。
Since the advent of anti-retroviral therapy, patients with HIV are living longer, and in the year 2015, over half of those infected with the virus will be older than age 50. Moreover, as the general aging population continues to grow, more elderly individuals will become newly infected with HIV. Older patients with HIV contribute to high numbers of initial and rehospitalizations, have longer lengths of hospital day stays, and are at increased risk of death compared to younger patients with HIV and those without HIV. Age-related comorbidities can be exaggerated in HIV-positive patients on and off therapy. Furthermore, signs and symptoms of HIV and AIDS may mimic features seen in the normal aging process of older adults. Internists caring for patients in inpatient settings will be expected to care for and diagnose increasing numbers of older patients with HIV. This will be critical for improving quality of patient care, reducing morbidity and mortality, and managing newly diagnosed patients earlier in the disease course while reducing spread of the virus. Internists should be central leaders in the development of targeted and non-targeted HIV screening efforts in inpatient general medicine wards.