THE HETEROGENEITY OF PARKINSONS-DISEASE - CLINICAL AND PROGNOSTIC IMPLICATIONS

THE HETEROGENEITY OF PARKINSONS-DISEASE - CLINICAL AND PROGNOSTIC IMPLICATIONS
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DOI:
10.1212/wnl.35.4.522
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发表时间:
1985-01-01
期刊:
影响因子:
9.9
通讯作者:
PIROZZOLO, FJ
PIROZZOLO, FJ
中科院分区:
医学1区
文献类型:
--
作者:
ZETUSKY, WJ;JANKOVIC, J;PIROZZOLO, FJ

文献摘要

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In 334 patients with idiopathic Parkinson''s disease, deterioration in mental status paralleled severity of bradykinesis, postural instability and gait difficulty. Tremor was relatively independent of the other cardinal signs and was associated with relative preservation of mental status, earlier age at onset, family history of parkinsonism and more favorable prognosis. There seem to be at least 2 Parkinson''s subgroups; 1 with postural instability and gait difficulty and another with tremor as the dominant feature.