Fusogenic metallosupramolecular brush vesicles.
Fusogenic metallosupramolecular brush vesicles.
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DOI：
10.1021/la303008c
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发表时间：
2012-10
期刊：
影响因子：
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通讯作者：
Lipeng He;Shuai Bi;Hui Wang;B. Ma;Weisheng Liu;W. Bu
中科院分区：
文献类型：
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作者：
Lipeng He;Shuai Bi;Hui Wang;B. Ma;Weisheng Liu;W. Bu
阳离子金属超分子聚电解质(Fe-MSP)与磺酸盐端基聚合物的静电结合可形成金属超分子刷(MSB)。得到的MSB在氯仿/甲醇(v/v=1：1)混合溶剂中可以自组装成泡状结构。刚性杆状Fe-MSP链必须弯曲以形成囊泡，这伴随着侧向张力的存在，从而诱导自发的囊泡融合，融合时间为1小时。对于这一更长的融合过程，在透射电子显微镜下可以清楚地看到箭头状的突起、柄状的中间体和半融合的横隔膜。完全融合成更大的囊泡可以显著释放侧向张力。
The electrostatic combination of a cationic metallosupramolecular polyelectrolyte (Fe-MSP) with sulfonate-terminated polymers leads to the formation of metallosupramolecular brushes (MSBs). The resulting MSBs can self-assemble into vesicular structures in chloroform/methanol (v/v = 1:1) mixture solvents. The rigid-rod Fe-MSP chain has to bend for the formation of the vesicles, which accompanies the presence of a lateral tension and thus induces a spontaneous vesicle fusion with an hour-scale fusion time. For this much longer fusion process, the arrow-like protrusion, stalk-like intermediate, and hemifusion diaphragm are clearly observed by transmission electron microscopy. The complete fusion into larger vesicles significantly releases the lateral tension.