Preeclampsia; short and long-term consequences for mother and neonate
Preeclampsia; short and long-term consequences for mother and neonate
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DOI：
10.1016/j.earlhumdev.2016.09.007
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发表时间：
2016-11-01
影响因子：
2.5
通讯作者：
de Groot, Christianne J. M.
中科院分区：
文献类型：
--
作者：
Bokslag, Anouk;van Weissenbruch, Mirjam;de Groot, Christianne J. M.
先兆子痫是一种常见的妊娠期特异性疾病，表现为高血压和多种器官衰竭，包括肾、肝和肺功能障碍。目前，子痫前期唯一确定的治疗方法是终止妊娠，娩出新生儿和胎盘。对于在妊娠的早产阶段患有轻度先兆子痫的妇女，期待治疗通常被指示以改善胎儿成熟度，通常需要母亲进行药物治疗。在过去的几十年里，越来越多的证据表明，先兆子痫的潜在机制，内皮疾病，不仅限于怀孕，但在以后的生活中增加心血管风险。在这篇综述中，我们提出了最新的见解，在先兆子痫的重点对胎儿的影响，后代的短期和长期的结果，长期的结果与先兆子痫的历史的妇女。(C)2016爱思唯尔爱尔兰有限公司版权所有。
Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life. In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia. (C) 2016 Elsevier Ireland Ltd. All rights reserved.