Configuration of the action observation network depends on the goals of the observer
Configuration of the action observation network depends on the goals of the observer
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DOI：
10.1016/j.neuropsychologia.2023.108704
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发表时间：
2023-11-04
期刊：
影响因子：
2.6
通讯作者：
Grossman，Emily D.
中科院分区：
文献类型：
--
作者：
Zhou，Xiaojue;Stehr，Daniel A.;Grossman，Emily D.
观察他人的行为需要一个核心动作观察网络（AON），其中包括双侧额下皮层（IFC）、颞上沟（pSTS）和顶下小叶（IPL）（Caspers et al., 2010）。 AON 中的每个区域都具有异质的功能属性，包括表示行动的感知属性、预测行动结果以及对行动者的目标进行推断。重要的是，最近的证据表明，当关注演员的运动学时，pSTS 内的神经表征会变得更加尖锐，从而自上而下引导的注意力会重塑潜在的神经表征。在这项研究中，我们评估了注意力如何改变 AON 作为一个系统内的网络连接。线索将参与者的注意力引导到短动作动画中描述的目标、运动学或身份，同时通过功能磁共振成像测量大脑反应。我们确定了 AON 内的那些地块具有按任务调节的功能连接。结果表明，在行动观察过程中，右侧 pSTS 和右侧 IFC 以及双边扩展 STS (STS+) 之间的连接受到调节，因此当参与者关注行动而不是目标时，连接会得到加强。这一发现与单变量结果形成鲜明对比，单变量结果显示，除了右 IFC 之外，这些大脑区域没有单变量调节。使用 Yeo 等人定义的功能网络。 （2011），我们确定了受注意力调节的部分主要由额顶控制网络和默认模式网络组成。这些结果与从 IFC 执行系统到 pSTS 的自上而下反馈模型一致，并暗示当关注全身运动学时，用于动作观察的右偏双通路模型。
Observing the actions of others engages a core action observation network (AON) that includes the bilateral inferior frontal cortex (IFC), posterior superior temporal sulcus (pSTS) and inferior parietal lobule (IPL) (Caspers et al., 2010). Each region in the AON has functional properties that are heterogeneous and include representing the perceptual properties of action, predicting action outcomes and making inferences as to the goals of the actor. Critically, recent evidence shows that neural representations within the pSTS are sharpened when attending to the kinematics of the actor, such that the top-down guided attention reshapes underlying neural representations. In this study we evaluate how attention alters network connectivity within the AON as a system. Cues directed participant's attention to the goal, kinematics, or identity depicted in short action animations while brain responses were measured by fMRI. We identified those parcels within the AON with functional connectivity modulated by task. Results show that connectivity between the right pSTS and right IFC, and bilateral extended STS (STS+) were modulated during action observation such that connections were strengthened when the participant was attending to the action than goal. This finding is contrasted by the univariate results, which no univariate modulations in these brain regions except for right IFC. Using the functional networks defined by Yeo et al. (2011), we identified the parcels that are modulated by the attention to consist mainly of the fronto-parietal control network and default mode networks. These results are consistent with models of top-down feedback from executive system in the IFC to pSTS and implicates a right lateralized dual pathway model for action observation when focused on whole-body kinematics.