PRESSORECEPTOR-AUTONOMIC OSCILLATION - A PROBABLE CAUSE OF VASOMOTOR WAVES
PRESSORECEPTOR-AUTONOMIC OSCILLATION - A PROBABLE CAUSE OF VASOMOTOR WAVES
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DOI：
10.1152/ajplegacy.1951.165.1.158
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发表时间：
1951-01-01
影响因子：
--
通讯作者：
HARRIS, JW
中科院分区：
文献类型：
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作者：
GUYTON, AC;HARRIS, JW
一项对狗的血管波的研究表明，阻断压力感受器系统或交感神经系统的因素将导致血管波消失。压力感受器反射的反应周期具有适当的持续时间，可以解释在血管波中观察到的振荡周期。简要讨论了调节系统中的振荡理论。压力感受器-自主神经反射系统满足振荡的两个基本条件，即，负反射和电路中的时间延迟。压力感受器-自主神经振荡可以解释如下：血压升高;这刺激了压力感受器;交感神经被抑制，迷走神经被兴奋;血压福尔斯下降。这就减少了压力感受器的兴奋;交感神经从抑制中释放出来，迷走神经不再兴奋;血压再次升高;这个循环无限期地重复下去，直到某种抑制因素介入。根据反射驱动力和阻尼因子的相对功率，这种振荡可以以渐增、持续或阻尼的形式存在。这3种形式中的每一种都已通过改变压力感受器-自主神经反射的驱动力在血管波中得到证实。
A study of vasomotor waves in dogs showed that factors which block either the pressoreceptor system or the sympathetic nervous system will cause vasomotor waves to disappear. The period of reaction of the pressoreceptor reflex is of proper duration to explain the period of oscillation noted in the vasomotor waves. The theory of oscillation in regulatory systems is briefly discussed. The pressoreceptor-autonomic nervous reflex system satisfies the 2 essential conditions for oscillation, i.e., a negative reflex and a time delay in the circuit. Pressoreceptor-autonomic oscillation may be explained as follows: The blood pressure rises; this stimulates the pressoreceptors; the sympathetics are inhibited and the vagi are excited; the blood pressure falls. This diminishes the excitation of the pressoreceptors; the sympathetics are released from their inhibition and the vagi are no longer excited; the blood pressure rises again; and the cycle repeats itself indefinitely until some dampening factor intervenes. Such oscillation may exist in the waxing, sustained, or dampened form depending on the relative power of the reflex driving force and the dampening factors. Each of these 3 forms has been demonstrated in vasomotor waves by varying the driving force of the pressoreceptor-autonomic reflex.