Fetal effects of combined spinal-epidural vs epidural labour analgesia: a prospective, randomised double-blind study
Fetal effects of combined spinal-epidural vs epidural labour analgesia: a prospective, randomised double-blind study
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DOI：
10.1111/anae.12602
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发表时间：
2014-05-01
期刊：
影响因子：
10.7
通讯作者：
Lyons, G. R.
中科院分区：
文献类型：
--
作者：
Patel, N. P.;El-Wahab, N.;Lyons, G. R.
我们比较了使用脊髓硬膜外联合镇痛或硬膜外镇痛开始分娩镇痛后的胎心率模式、阿普加评分和脐带气体值。 115 名在第一产程中要求椎管内镇痛的健康女性被随机分配接受脊髓-硬膜外联合镇痛 (n=62) 或硬膜外镇痛 (n=53)。根据国家指南，在椎管阻滞前 30 分钟和椎管阻滞后 60 分钟记录的胎心率痕迹被分类为正常、可疑或病理。脊髓-硬膜外联合组中分析了 61 条胎儿心率描记图，硬膜外组中分析了 52 条胎心率描记图。各组之间的胎心率模式、阿普加评分或脐动脉和静脉酸碱状态没有发现显着差异。然而，在椎管内硬膜外联合组和硬膜外组中，椎管内镇痛后异常胎心率模式的发生率显着增加（p
We have compared fetal heart rate patterns, Apgar scores and umbilical cord gas values following initiation of labour analgesia using either combined spinal-epidural or epidural. One hundred and fifteen healthy women requesting neuraxial analgesia in the first stage of labour were randomly assigned to receive either combined spinal-epidural (n=62) or epidural analgesia (n=53). Fetal heart rate traces, recorded for 30min before and 60min after neuraxial block, were categorised as normal, suspicious or pathological according to national guidelines. Sixty-one fetal heart rate tracings were analysed in the combined spinal-epidural group and 52 in the epidural group. No significant differences were found in fetal heart rate patterns, Apgar scores or umbilical artery and vein acid-base status between groups. However, in both combined spinal-epidural and epidural groups, there was a significant increase in the incidence of abnormal fetal heart rate patterns following neuraxial analgesia (p