Causes of Fever in Rural Southern Laos

Causes of Fever in Rural Southern Laos
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DOI:
10.4269/ajtmh.14-0772
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发表时间:
2015-09-01
影响因子:
3.3
通讯作者:
Newton, Paul N.
Newton, Paul N.
中科院分区:
医学4区
文献类型:
--
作者:
Mayxay, Mayfong;Sengvilaipaseuth, Onanong;Newton, Paul N.

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由于缺乏实验室设施,老挝人民民主共和国(老挝)农村地区发烧的病因直到最近仍不清楚。我们进行了一项研究,以确定老挝南部沙湾拿吉省229名非疟疾患者的发热原因; 52%有至少一种诊断的证据(45%为单一感染,7%为明显的多重感染)。在仅有一种诊断的患者中,登革热(30.1%)最常见,其次是钩端螺旋体病(7.0%)、日本脑炎病毒感染(3.5%)、恙虫病(2.6%)、斑点热群感染(0.9%)、未指明的黄病毒感染(0.9%)和鼠斑疹伤寒(0.4%)。我们将讨论与这些发现有关的发热的经验性治疗。
The etiology of fever in rural Lao People's Democratic Republic (Laos) has remained obscure until recently owing to the lack of laboratory facilities. We conducted a study to determine the causes of fever among 229 patients without malaria in Savannakhet Province, southern Laos; 52% had evidence of at least one diagnosis (45% with single and 7% with apparent multiple infections). Among patients with only one diagnosis, dengue (30.1%) was the most common, followed by leptospirosis (7.0%), Japanese encephalitis virus infection (3.5%), scrub typhus (2.6%), spotted fever group infection (0.9%), unspecified flavivirus infection (0.9%), and murine typhus (0.4%). We discuss the empirical treatment of fever in relation to these findings.