Neonatal Necrotizing Enterocolitis -Inflammation and Intestinal Immaturity.
Neonatal Necrotizing Enterocolitis -Inflammation and Intestinal Immaturity.
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DOI：
10.2174/187152309789152020
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发表时间：
2009-09
影响因子：
--
通讯作者：
Claud EC
中科院分区：
文献类型：
--
作者：
Claud EC
Neonatal necrotizing enterocolitis is a devastating inflammatory bowel disease of premature infants. The pathogenesis remains incompletely understood and there is no specific treatment. Efforts are ongoing to understand aspects of intestinal immaturity which contribute to susceptibility to this disease. This review focuses on bacterial colonization patterns, intestinal barrier function, and inflammatory responses of immature enterocytes leading to a unique vulnerability of the preterm gut. In addition the possible therapeutic potential of factors in human milk and probiotic bacteria is discussed.
