Development of Highly Sensitive Immunochromatographic Detection Kit for Seasonal Influenza Virus Using Silver Amplification
Development of Highly Sensitive Immunochromatographic Detection Kit for Seasonal Influenza Virus Using Silver Amplification
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利用银扩增技术开发季节性流感病毒高灵敏免疫层析检测试剂盒
DOI：
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
Takayoshi Oyamada
中科院分区：
文献类型：
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作者：
Mikinaga Mori;J. Katada;H. Chiku;Kentaro Nakamura;Takayoshi Oyamada
应用我们的光技术，我们使用 50 nm 金颗粒作为催化剂，成功地产生了超过 10 μm 的银颗粒，这通常用于市售流感诊断试剂盒。放大的银颗粒比金纳米颗粒更容易看到 1,000 倍。利用该扩增技术，我们将流感检测试剂盒“FUJI DRI-CHEM IMMUNO AG Cartridge FluAB”以及自动判断流感感染阳性或阴性的光密度分析机“FUJI DRI-CHEM IMMUNO AG1”商业化。
Applying our photo technology, we succeeded in generating silver particles exceeding 10 μm by using 50 nm gold particles as catalysts, which are commonly used in commercially available influenza diagnostic kits. The amplified silver particles are 1,000 times easier to see than gold nano-particles. We have commercialized the influenza detection kit, named “FUJI DRI-CHEM IMMUNO AG cartridge FluAB”, and the densitometry analysis machine to determine automatically positive or negative for influenza infection, named “FUJI DRI-CHEM IMMUNO AG1”, using this amplification technology.