Neurobehavioural correlates of body mass index and eating behaviours in adults: a systematic review.
Neurobehavioural correlates of body mass index and eating behaviours in adults: a systematic review.
复制标题
成人体重指数和饮食行为的神经行为相关性：系统评价。
DOI：
10.1016/j.neubiorev.2012.11.008
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发表时间：
2013
影响因子：
8.2
通讯作者：
Fellows,LesleyK
中科院分区：
文献类型：
--
作者：
Vainik,Uku;Dagher,Alain;Dubé,Laurette;Fellows,LesleyK
全球范围内肥胖症的增加促使人们做出了许多努力来了解饮食行为的调节和潜在的大脑机制。这些机制可以通过神经行为的措施来研究。在这里，我们系统地回顾这些努力，评估神经认知测试和人格问卷的基础上：（a）与肥胖和饮食行为的一致关系，（B）可靠性。我们还考虑了这些措施的潜力，以阐明这些个体差异背后的大脑机制。66个神经认知任务进行了检查。不到11%，主要是执行功能和食物动机的措施，产生了重复和可靠的效果。几种不同的人格问卷一直与BMI相关。然而，进一步的分析发现，这些问卷中的许多与五因素人格模型中的责任心，外向性和神经质密切相关。神经认知测试和人格问卷都表明，与肥胖个体差异相关的关键神经系统是支持自我控制的外侧前额叶结构和与食物动机有关的纹状体区域。这一审查可以指导选择最高收益的神经行为措施，为未来的研究。
The worldwide increase in obesity has spurred numerous efforts to understand the regulation of eating behaviours and underlying brain mechanisms. These mechanisms can affordably be studied via neurobehavioural measures. Here, we systematically review these efforts, evaluating neurocognitive tests and personality questionnaires based on: (a) consistent relationship with obesity and eating behaviour, and (b) reliability. We also considered the measures’ potential to shed light on the brain mechanisms underlying these individual differences. Sixty-six neurocognitive tasks were examined. Less than 11%, mainly measures of executive functions and food motivation, yielded both replicated and reliable effects. Several different personality questionnaires were consistently related to BMI. However, further analysis found that many of these questionnaires relate closely to Conscientiousness, Extraversion and Neuroticism within the Five-Factor Model of personality. Both neurocognitive tests and personality questionnaires suggest that the critical neural systems related to individual differences in obesity are lateral prefrontal structures underpinning self-control and striatal regions implicated in food motivation. This review can guide selection of the highest yield neurobehavioural measures for future studies.