Variational Reconstruction of Left Cardiac Structure from CMR Images.
Variational Reconstruction of Left Cardiac Structure from CMR Images.
复制标题
根据 CMR 图像对左心脏结构进行变分重建
DOI：
10.1371/journal.pone.0145570
复制
发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Zhong L
中科院分区：
文献类型：
--
作者：
Wan M;Huang W;Zhang JM;Zhao X;Tan RS;Wan X;Zhong L
心血管疾病（CVD）占美国总死亡人数的17%，是世界上主要的死亡原因。医学影像技术的发展使心脏解剖和功能的定量评价成为可能。心脏建模是定量分析的前提。在这项研究中，提出了一种新的方法来重建左心脏结构的多平面心脏磁共振（CMR）图像和轮廓。常规CMR检查，获取长轴和短轴图像。经过培训的技术人员描绘了内镜轮廓。将多组二维轮廓投影到基于患者的三维坐标系中并彼此配准。对配准后的点集进行合并，采用基于Delaunay三角剖分和图割的变分曲面重建算法。对生成的三角化曲面进行进一步的后处理。通过计算重建模型与人工绘制的长轴轮廓线之间的重叠率，对我们的方法进行了定量评价，验证了我们的方法。我们设想这种方法可以被放射技师和心脏病学家用来诊断和评估患有各种心脏疾病的患者的心脏功能。
Cardiovascular Disease (CVD), accounting for 17% of overall deaths in the USA, is the leading cause of death over the world. Advances in medical imaging techniques make the quantitative assessment of both the anatomy and function of heart possible. The cardiac modeling is an invariable prerequisite for quantitative analysis. In this study, a novel method is proposed to reconstruct the left cardiac structure from multi-planed cardiac magnetic resonance (CMR) images and contours. Routine CMR examination was performed to acquire both long axis and short axis images. Trained technologists delineated the endocardial contours. Multiple sets of two dimensional contours were projected into the three dimensional patient-based coordinate system and registered to each other. The union of the registered point sets was applied a variational surface reconstruction algorithm based on Delaunay triangulation and graph-cuts. The resulting triangulated surfaces were further post-processed. Quantitative evaluation on our method was performed via computing the overlapping ratio between the reconstructed model and the manually delineated long axis contours, which validates our method. We envisage that this method could be used by radiographers and cardiologists to diagnose and assess cardiac function in patients with diverse heart diseases.