Procedural validity of the AUDADIS-5 depression, anxiety and post-traumatic stress disorder modules: Substance abusers and others in the general population

Procedural validity of the AUDADIS-5 depression, anxiety and post-traumatic stress disorder modules: Substance abusers and others in the general population
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DOI:
10.1016/j.drugalcdep.2015.03.027
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发表时间:
2015-07-01
影响因子:
4.2
通讯作者:
Grant, Bridget F.
Grant, Bridget F.
中科院分区:
医学2区
文献类型:
--
作者:
Hasin, Deborah S.;Shmulewitz, Dvora;Grant, Bridget F.

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背景:通过与临床再评估相比较,对一般人群中的抑郁、焦虑和创伤后应激障碍(PTSD)进行非专业的、完全结构化的评估的程序有效性,以及在目前经常滥用药物的人和其他人之间是否存在差异,人们知之甚少。我们通过临床医生的重新访谈,评估了DSM-5版酒精使用障碍和相关残疾访谈量表(AUDADIS-5)对这些障碍评估的程序效度。方法:在国家酒精及相关条件流行病学调查III(NESARC-III)的受访者中进行重测设计:(264名目前经常滥用药物的人,447名其他人)。对AUDADIS-5结果视而不见的临床医生进行了DSM-5版(PRISM-5)的半结构式物质和精神疾病精神病学研究访谈。诊断的Kappa(K)和维度测量(DSM-5症状或标准计数)的组内相关系数(ICC)表示AUDADIS-5/PRISM-5的一致性。结果:DSM-5抑郁障碍、焦虑症和创伤后应激障碍的AUDADIS-5和PRISM-5的一致性总体上为中到中度(k=0.24~0.59),维度上的一致性较好(ICC=0.53~0.81)。结论:AUDADIS-5/PRISM-5一致性表明AUDADIS-5在药物滥用者和其他人群中具有程序效度,提示AUDADIS-5诊断DSM-5抑郁、焦虑和创伤后应激障碍在流行病学研究中对两组都具有信息性。维度测量的更强一致性支持当前向维度精神病理学测量的趋势,这表明此类测量为NESARC-III和其他数据集的研究提供了重要信息,可能也用于临床目的。(C)爱思唯尔爱尔兰有限公司出版的2015年。
Background: Little is known about the procedural validity of lay-administered, fully-structured assessments of depressive, anxiety and post-traumatic stress (PTSD) disorders in the general population as determined by comparison with clinical re-appraisal, and whether this differs between current regular substance abusers and others. We evaluated the procedural validity of the Alcohol Use Disorder and Associated Disabilities Interview Schedule, DSM-5 Version (AUDADIS-5) assessment of these disorders through clinician re-interviews.Methods: Test-retest design among respondents from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III): (264 current regular substance abusers, 447 others). Clinicians blinded to AUDADIS-5 results administered the semi-structured Psychiatric Research Interview for Substance and Mental Disorders, DSM-5 version (PRISM-5). AUDADIS-5/PRISM-5 concordance was indicated by kappa (k) for diagnoses and intraclass correlation coefficients (ICC) for dimensional measures (DSM-5 symptom or criterion counts). Results were compared between current regular substance abusers and others.Results: AUDADIS-5 and PRISM-5 concordance for DSM-5 depressive disorders, anxiety disorders and PTSD was generally fair to moderate (k = 0.24-0.59), with concordance on dimensional scales much better (ICC = 0.53-0.81). Concordance differed little between regular substance abusers and others.Conclusions: AUDADIS-5/PRISM-5 concordance indicated procedural validity for the AUDADIS-5 among substance abusers and others, suggesting that AUDADIS-5 diagnoses of DSM-5 depressive, anxiety and PTSD diagnoses are informative measures in both groups in epidemiological studies. The stronger concordance on dimensional measures supports the current movement toward dimensional psychopathology measures, suggesting that such measures provide important information for research in the NESARC-III and other datasets, and possibly for clinical purposes as well. (C) 2015 Published by Elsevier Ireland Ltd.