Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint
Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint
复制标题
DOI：
10.1021/np010020u
复制
发表时间：
2001-08-01
影响因子：
5.1
通讯作者：
Clardy, J
中科院分区：
文献类型：
--
作者：
Wagenaar, MM;Clardy, J
在生物测定的指导下，从濒危薄荷Dicerandra rutescens的内生真菌--长穗拟态木霉的培养物中分离得到了麦饭酚A、B和C。通过广泛的核磁共振和HRFABMS实验，这些新的黄色抗生素和细胞毒性化合物被鉴定为2，2‘-二聚四氢呋喃。
Bioassay-guided fractionation of the organic extract from a culture of Phomopsis longicolla, an endophytic fungus of the endangered mint Dicerandra frutescens, led to the isolation of dicerandrols A, B, and C. Extensive NMR and HRFABMS experiments were used to identify these new yellow antibiotic and cytotoxic compounds as 2,2 ' -dimeric tetrahydroxanthones.