Short sleep duration and weight gain: A systematic review
Short sleep duration and weight gain: A systematic review
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DOI：
10.1038/oby.2007.118
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发表时间：
2008-03-01
期刊：
影响因子：
6.9
通讯作者：
Hu, Frank B.
中科院分区：
文献类型：
--
作者：
Patel, Sanjay R.;Hu, Frank B.
目的：最近的肥胖流行伴随着慢性睡眠剥夺的增加。生理学研究表明，睡眠不足可能通过影响食欲、体力活动和/或体温调节来影响体重。方法和步骤：应用MEDLINE数据库检索1966年至2007年1月发表的所有文献，检索词“睡眠”和(“持续时间”或“小时”或“小时”)和(“肥胖”或“体重”)。通过查阅书目和联系该领域的专家，确定了其他参考文献。研究报告了睡眠时间与至少一项体重测量之间的关系。结果：确定了36篇文章(31篇横断面研究，5篇前瞻性研究，0篇实验)。在对儿童的横断面和队列研究中的发现表明，睡眠时间短与当前和未来的肥胖有强烈和一致的联系。成人横断面分析的结果更加混杂，23项研究中有17项支持睡眠时间短和体重增加之间的独立联系。相比之下，所有三项针对成年人的纵向研究都发现，睡眠时间短与未来体重之间存在正相关。这种关系似乎随着年龄的增长而减弱。讨论：睡眠时间短似乎与体重增加独立相关，特别是在较年轻的年龄组。然而，主要的研究设计限制排除了明确的结论。为了更好地确定睡眠剥夺与肥胖的因果关系，需要对睡眠时间的客观测量、对睡眠和体重的重复评估以及操纵睡眠的实验研究设计进行进一步的研究。
objective: The recent obesity epidemic has been accompanied by a parallel growth in chronic sleep deprivation. Physiologic studies suggest sleep deprivation may influence weight through effects on appetite, physical activity, and/or thermoregulation. This work reviews the literature regarding short sleep duration as an independent risk factor for obesity and weight gain.Methods and Procedures: A literature search was conducted for all articles published between 1966 and January 2007 using the search "sleep" and ("duration" or "hour" or "hours") and ("obesity" or "weight") in the MEDLINE database. Additional references were identified by reviewing bibliographies and contacting experts in the field. Studies reporting the association between sleep duration and at least one measure of weight were included.Results: Thirty-six publications (31 cross-sectional, 5 prospective, and 0 experimental) were identified. Findings in both cross-sectional and cohort studies of children suggested short sleep duration is strongly and consistently associated with concurrent and future obesity. Results from adult cross-sectional analyses were more mixed with 17 of 23 studies supporting an independent association between short sleep duration and increased weight. In contrast, all three longitudinal studies in adults found a positive association between short sleep duration and future weight. This relationship appeared to wane with age.Discussion: Short sleep duration appears independently associated with weight gain, particularly in younger age groups. However, major study design limitations preclude definitive conclusions. Further research with objective measures of sleep duration, repeated assessments of both sleep and weight, and experimental study designs that manipulate sleep are needed to better define the causal relationship of sleep deprivation on obesity.