Cervical cancer control in HIV-infected women: Past, present and future.
Cervical cancer control in HIV-infected women: Past, present and future.
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DOI：
10.1016/j.gore.2017.07.009
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发表时间：
2017-08
影响因子：
1.2
通讯作者：
Simonds H
中科院分区：
文献类型：
--
作者：
Ghebre RG;Grover S;Xu MJ;Chuang LT;Simonds H
自1981年首次确认获得性免疫缺陷综合征（艾滋病）以来，人类免疫缺陷病毒（HIV）阳性女性中宫颈癌的负担有所增加。抗逆转录病毒疗法（ART）的引入降低了机会性感染的风险并提高了总体生存率。感染HIV的女性寿命更长。人乳头瘤病毒（HPV）疫苗的引入、宫颈癌筛查和早期诊断为降低宫颈癌相关死亡率提供了机会。为了实现2030年可持续发展目标中降低非传染性疾病死亡率的目标，需要更加关注撒哈拉以南非洲（SSA）负担较重的国家。尽管撒哈拉以南非洲资源有限，但仍存在改善癌症控制的机会。本文综述了HIV阳性女性宫颈癌控制方面的进展。
女性宫颈癌和HIV感染的负担集中在撒哈拉以南非洲。
本综述重点介绍了HIV阳性女性中的宫颈癌控制项目。
在HIV阳性女性的宫颈癌控制方面存在知识空白。
Since the initial recognition of acquired immunodeficiency syndrome (AIDS) in 1981, an increased burden of cervical cancer was identified among human immunodeficiency virus (HIV)-positive women. Introduction of antiretroviral therapy (ART) decreased risks of opportunistic infections and improved overall survival. HIV-infected women are living longer. Introduction of the human papillomavirus (HPV) vaccine, cervical cancer screening and early diagnosis provide opportunities to reduce cervical cancer associated mortality. In line with 2030 Sustainable Development Goals to reduce mortality from non-communicable diseases, increased efforts need to focus on high burden countries within sub-Saharan Africa (SSA). Despite limitations of resources in SSA, opportunities exist to improve cancer control. This article reviews advancements in cervical cancer control in HIV-positive women. The burden of cervical cancer and HIV-infection in women is concentrated in sub-Saharan Africa. Cervical cancer control programs among HIV-positive women are highlighted in this review. Gaps in knowledge exist in cervical cancer control in HIV-positive women.