Retinitis pigmentosa associated with a defect in the production of interferon-gamma.
Retinitis pigmentosa associated with a defect in the production of interferon-gamma.
复制标题
色素性视网膜炎与干扰素-γ产生缺陷有关。
DOI:
10.1016/s0002-9394(14)71920-8
复制
发表时间:
1983
影响因子:
4.2
通讯作者:
D. Newsome
中科院分区:
文献类型:
--
作者:
J. Hooks;B. Detrick‐Hooks;S. Geis;D. Newsome
Peripheral lymphocytes from patients with retinitis pigmentosa have a deficiency in their ability to produce the lymphokine, interferon-gamma. In 12 patients we found that peripheral leukocytes produced subnormal levels of interferon-gamma. These findings suggested that altered immune reactivity is one of the abnormalities associated with retinitis pigmentosa.