Relaxation times of breast tissue at 1.5T and 3T measured using IDEAL
Relaxation times of breast tissue at 1.5T and 3T measured using IDEAL
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DOI：
10.1002/jmri.20469
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发表时间：
2006-01-01
影响因子：
4.4
通讯作者：
Glover, GH
中科院分区：
文献类型：
--
作者：
Rakow-Penner, R;Daniel, B;Glover, GH
目的：准确测量乳腺纤维腺组织和脂肪在1.5T和3T的T1和T2，并用回声不对称最小二乘迭代分解成像方法观察纤维腺组织和脂肪混合物对松弛速率的部分体积效应。材料和方法：测量5例健康女性右乳房1.5T和3T的T1和T2值。使用两种序列收集T1数据：无理想的反转恢复序列和有理想的反转恢复序列。使用Hahn Echo扫描收集T2数据。结果：从1.5T到3T，脂肪(21%)和腺体组织(17%)的T1均增加。因此，乳房方案在3T时的TR和TI应相应延长。从1.5T到3T，两种组织的SNR都增加了一倍以上。理想的成像显示了脂肪和腺组织的部分体积效应对测量独立组织类型的松弛速率的影响。结论：分离的脂肪和水图像可以更精确地测量脂肪中的脂肪成分和纤维腺组织中的水成分。
Purpose: To accurately measure T1 and T2 of breast fibroglandular tissue and fat at 1.5T and 3T, and note the partial volume effects of the admixture of fibroglandular tissue and fat on the relaxation rates using an approach termed iterative decomposition of water and fat with echo asymmetry and least squares estimation (IDEAL) imaging.Materials and Methods: T1 and T2 values were measured on the right breasts of five healthy women at 1.5T and 3T. T1 data were collected using two sequences: inversion recovery without IDEAL, and inversion recovery with IDEAL. T2 data were collected using Hahn Echo scans. SNR and CNR analyses were conducted on collected data.Results: T1 increased for both fat (21%) and glandular tissue (17%) from 1.5T to 3T. Thus, the TR and TI of breast protocols at 3T should be lengthened accordingly. SNR more than doubled for both tissue types from 1.5T to 3T. IDEAL imaging demonstrated the partial volume effects of fat and glandular tissue on measuring relaxation rates of independent tissue types.Conclusion: With separated fat and water images, more precise measurements can be made for the lipid component in fat, and the water component in fibroglandular tissue.