Chloramphenicol acetyltransferase should not provide methanogens with resistance to chloramphenicol.
Chloramphenicol acetyltransferase should not provide methanogens with resistance to chloramphenicol.
复制标题
氯霉素乙酰转移酶不应使产甲烷菌对氯霉素产生抗性。
DOI：
10.1128/aem.47.4.868-869.1984
复制
发表时间：
1984
影响因子：
4.4
通讯作者：
Reeve,JN
中科院分区：
文献类型：
--
作者：
Beckler,GS;Hook,LA;Reeve,JN
氯霉素-3-乙酸酯抑制了四种甲烷菌的生长，因此，引入氯霉素乙酰转移酶编码基因不应使这些甲烷菌产生氯霉素抗性。氯霉素的芳基硝基的还原产生了一种化合物，该化合物不抑制这些产甲烷菌的生长。
Growth of the four methanogens investigated was inhibited by chloramphenicol-3-acetate; therefore, introduction of chloramphenicol acetyltransferase-encoding genes should not confer chloramphenicol resistance on these methanogens. Reduction of the aryl nitro group of chloramphenicol produced a compound which did not inhibit the growth of these methanogens.