Longitudinal trends in major cardiovascular risk factors in the Czech population between 1985 and 2007/8. Czech MONICA and Czech post-MONICA
Longitudinal trends in major cardiovascular risk factors in the Czech population between 1985 and 2007/8. Czech MONICA and Czech post-MONICA
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DOI：
10.1016/j.atherosclerosis.2010.04.007
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发表时间：
2010-08-01
期刊：
影响因子：
5.3
通讯作者：
Lanska, Vera
中科院分区：
文献类型：
--
作者：
Cifkova, Renata;Skodova, Zdenka;Lanska, Vera
目的：本研究的目的是评估捷克共和国有代表性的人群中主要心血管危险因素的纵向趋势。方法：在1985年(n=2570)、1988年(n=2768)和1992年(n=2343)的6个捷克地区，在世界卫生组织Monica项目范围内对心血管危险因素进行了三次横断面调查。在1997/98、2000/01和2007/08年度，又在6个原城区(分别为1990年、2055和2246)进行了3次心血管危险因素筛查(1%随机抽样，年龄在25岁-之间，平均年龄为45岁)。结果：在22/23年间，男性吸烟率显著下降(从45.0%下降到30.5%；p<；0.001)，女性吸烟习惯没有改变。男性BMI增加，女性BMI无变化。无论男女，收缩压和舒张压均显著下降，而高血压患病率仅在女性中下降。人们对高血压的认识也有所提高，接受降压药治疗的男女比例都有所上升。无论男女，高血压控制都有所改善。总胆固醇在男女人群中均有显著下降(男性：从6.21±1.29降至5.29±1.10 mm ol/L；p<；0.001；女性：从6.18±-1.26降至5.30±1.06 mm ol/L；p<；0.001)。(C)2010爱思唯尔爱尔兰有限公司。保留所有权利。
Objective: The aim of our study was to assess longitudinal trends in major CV risk factors in a representative population sample of the Czech Republic.Methods: Three cross-sectional surveys of CV risk factors were conducted within the WHO MONICA project in six Czech districts in 1985 (n = 2570), 1988 (n = 2768), and 1992 (n = 2343). In 1997/98, 2000/01, and 2007/08, another three screenings for CV risk factors (a 1% random sample, aged 25-64, mean age 45 years) were conducted in the six original districts (n = 1990; 2055; and 2246, respectively).Results: Over a period of 22/23 years, there was a significant decrease in the prevalence of smoking in males (from 45.0 to 30.5%; p < 0.001) and no change in smoking habits in females. BMI increased in males and did not change in females. Both systolic and diastolic blood pressure decreased significantly in both genders, while the prevalence of hypertension declined only in females. Awareness of hypertension also rose as did the proportion of individuals treated by antihypertensive drugs in both genders. Hypertension control improved in either gender. A remarkable drop in total cholesterol was seen in both sexes (males: from 6.21 +/- 1.29 to 5.29 +/- 1.10 mmol/L; p < 0.001; females: from 6.18 +/- 1.26 to 5.30 +/- 1.06 mmol/L; p < 0.001).Conclusions: The striking improvement in CV risk factors documented between 1985 and 2007/8 most likely contributed to the decrease in CV mortality in the Czech Republic. (C) 2010 Elsevier Ireland Ltd. All rights reserved.