A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)
A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)
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DOI：
10.1016/j.jalz.2019.08.192
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发表时间：
2019-12-01
影响因子：
14
通讯作者：
Schneiderman, Neil
中科院分区：
文献类型：
--
作者：
Gonzalez, Hector M.;Tarraf, Wassim;Schneiderman, Neil
西班牙裔/拉丁裔是美国最大的民族/种族群体，患有阿尔茨海默病和相关痴呆症（ADRD）的风险很高。然而，与其他民族/种族群体相比，不同拉丁美洲人对ADRD的了解很少，而且研究不足或未研究，这使得该国对未来几十年的重大人口变化准备不足。这篇观点文章的主要目的是为推进拉丁美洲ADRD知识提供一个新的研究框架，包括拉丁美洲健康，老龄化和ADRD的独特社会文化，心脏代谢和基因组方面。此外，我们描述了一些研究的挑战，在拉丁美洲ADRD研究的进展。最后，我们提出了拉丁美洲人的研究-神经认知老化的调查（SOL-INCA）作为一个例子，实现这个新的框架，推进拉丁美洲ADRD研究。(C)2019年，阿尔茨海默氏症协会。爱思唯尔公司出版All rights reserved.
Hispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups that leave the nation ill-prepared for major demographic shifts that lay ahead in coming decades. The primary purpose of this Perspectives article was to provide a new research framework for advancing Latino ADRD knowledge, encompassing the unique sociocultural, cardiometabolic, and genomic aspects of Latino health, aging, and ADRD. In addition, we describe some of the research challenges to progress in Latino ADRD research. Finally, we present the Study of Latinos - Investigation of Neurocognitive Aging (SOL-INCA) as an example of implementing this new framework for advancing Latino ADRD research. (C) 2019 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.