Melioidosis in southern Vietnam: Clinical surveillance and environmental sampling

Melioidosis in southern Vietnam: Clinical surveillance and environmental sampling
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DOI:
10.1086/313479
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发表时间:
1999-11-01
影响因子:
11.8
通讯作者:
Farrar, JJ
Farrar, JJ
中科院分区:
医学1区
文献类型:
--
作者:
Parry, CM;Wuthiekanun, V;Farrar, JJ

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从1992年至1998年,类鼻疽伯克霍尔德氏菌分离自胡志明市热带病中心(越南南部的传染病转诊中心)收治的发热患者的3653份血液培养物中,仅9份(0.25%)。从胡志明市辐射的5条主要道路沿线沿着的147个稻田中的407个地点采集土壤样品。从39个稻田(27%)的73个点(18%)分离到类鼻疽B,但从9个稻田(6%)的71个分离物中只有15个(21%)为强毒阿拉伯糖(ara)阴性生物型,除1个为ara阴性生物型的稻田外,其余稻田都与类鼻疽患者的家很近,胡志明市周围省份类鼻疽发病率低可能是由于ara阴性B分布有限所致。在这片土地上发现了假鼻疽
From 1992-1998, Burkholderia pseudomallei was isolated from only 9 (0.25%) of 3653 cultures of blood from febrile patients admitted to the Centre for Tropical Diseases in Ho Chi Minh City, an infectious disease referral center for southern Vietnam. Soil was sampled from 407 sites in 147 rice fields along the 5 major roads radiating from Ho Chi Minh City. B, pseudomallei was isolated from 73 sites (18%) in 39 rice fields (27%), but only 15 (21%) of the 71 isolates from 9 (6%) of 147 fields were the virulent L-arabinose (ara)-negative biotype, All except 1 of the fields with the ara-negative biotype were close to the homes of the patients with melioidosis, The low incidence of melioidosis in the provinces around Ho Chi Minh City may be explained by the restricted distribution of ara-negative B. pseudomallei in the soil in this area.