A Novel Staging System to Evaluate Cerebral Hypoperfusion in Patients With Moyamoya Disease
A Novel Staging System to Evaluate Cerebral Hypoperfusion in Patients With Moyamoya Disease
复制标题
评估烟雾病患者脑灌注不足的新型分期系统
DOI：
10.1161/strokeaha.118.022628
复制
发表时间：
2018-12-01
期刊：
影响因子：
8.3
通讯作者：
Zhao, Jizong
中科院分区：
文献类型：
--
作者：
Yin, Hu;Liu, Xingju;Zhao, Jizong
背景与目的：本研究的目的是通过一种新的分期系统来评估烟雾病患者的脑灌注，并探讨血管重化术治疗患者的灌注状态差异与临床结局之间的关系。方法：2009 - 2015年连续入组约506例患者。灌注状态通过分期系统评估，即基于ct灌注结果的梗死前期分期。比较出血患者（155例）和缺血患者（351例）不同灌注阶段的半球。采用改良Rankin量表评价患者预后。结果：入组506例患者中，灌注正常的半球229个（22.6%），I期72个（7.1%），II期205个（20.3%），III期308个（30.4%），IV期198个（19.6%）
Background and Purpose-The study goal was to evaluate cerebral perfusion in moyamoya patients with a novel staging system and investigate the association between differences of perfusion status and clinical outcomes in patients treated with revascularization.Methods-About 506 consecutive patients from 2009 to 2015 were enrolled. The perfusion status was evaluated by a staging system-the stage of preinfarction period based on the result of computed tomography perfusion. Hemisphere in different perfusion stage was compared between hemorrhagic patients (n=155) and ischemic patients (n=351). The modified Rankin Scale was applied to evaluate the prognosis of patients.Results-In the enrolled 506 patients: 229 hemispheres (22.6%) with normal perfusion, 72 hemispheres (7.1%) in stage I, 205 hemispheres (20.3%) in stage II, 308 hemispheres (30.4%) in stage III, and 198 hemispheres (19.6%) in stage IV. Significant difference was observed in stage distribution between hemorrhagic patients and ischemic patients (P