Minimal neuropsychological assessment of MS patients: A consensus approach
Minimal neuropsychological assessment of MS patients: A consensus approach
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DOI：
10.1076/clin.16.3.381.13859
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发表时间：
2002-08-01
影响因子：
3.9
通讯作者：
Munschauer, F
中科院分区：
文献类型：
--
作者：
Benedict, RHB;Fischer, JS;Munschauer, F
认知障碍在多发性硬化症（MS）中很常见，但在多发性硬化症诊所和神经病学实践中看到的患者并没有常规的神经心理学评估。在某种程度上，NP服务的不良利用可能归因于神经心理学家对评估多发性硬化症患者的最佳方法缺乏共识。2001年4月，多发性硬化症中心联盟（CMSC）召集了一个由神经心理学家和来自美国、加拿大、英国和澳大利亚的心理学家组成的专家小组。我们的目标是：(a)提出一种用于MS患者临床监测和研究的最小神经心理学（NP）检查，以及(b)确定未来改进MS患者NP评估的策略。小组回顾了有关多发性硬化症相关认知功能障碍的相关文献，考虑了与NP评估相关的心理测量因素，定义了多发性硬化症最小NP测试的目的和最佳特征，并根据现有文献对36种候选NP测试的心理测量和实用特性进行了评级。一个90分钟的NP组，MS认知功能最小评估（MACFIMS），从这个讨论中产生。MACFIMS由7个神经心理学测试组成，涵盖多发性硬化症常见的5个认知领域（处理速度/工作记忆、学习和记忆、执行功能、视觉空间处理和文字检索）。它由一项估计的病前认知能力的测量来补充。本文提出了评估可能会混淆NP数据解释的其他因素（如视觉/感觉/运动障碍、疲劳和抑郁）的建议，以及未来改进MS患者NP评估的策略。
Cognitive impairment is common in multiple sclerosis (MS), yet patients seen in MS clinics and neurologic practices are not routinely assessed neuropsychologically. In part, poor utilization of NP services may be attributed to a lack of consensus among neuropsychologists regarding the optimal approach for evaluating MS patients. An expert panel composed of neuropsychologists and psychologists from the United States, Canada, United Kingdom, and Australia was convened by the Consortium of MS Centers (CMSC) in April, 2001. Our objectives were to: (a) propose a minimal neuropsychological (NP) examination for clinical monitoring of MS patients and research, and (b) identify strategies for improving NP assessment of MS patients in the future. The panel reviewed pertinent literature on MS-related cognitive dysfunction, considered psychometric factors relevant to NP assessment, defined the purpose and optimal characteristics of a minimal NP examination in MS, and rated the psychometric and practical properties of 36 candidate NP measures based on available literature. A 90-minute NP battery, the Minimal Assessment of Cognitive Function in MS (MACFIMS), emerged from this discussion. The MACFIMS is composed of seven neuropsychological tests, covering five cognitive domains commonly impaired in MS (processing speed/working memory, learning and memory, executive function, visual-spatial processing, and word retrieval). It is supplemented by a measure of estimated premorbid cognitive ability. Recommendations for assessing other factors that may potentially confound interpretation of NP data (e.g., visual/sensory/motor impairment, fatigue, and depression) are offered, as well as strategies for improving NP assessment of MS patients in the future.