Breast cancer in Iran: An epidemiological review

Breast cancer in Iran: An epidemiological review
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DOI:
10.1111/j.1524-4741.2007.00446.x
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发表时间:
2007-07-01
期刊:
影响因子:
2.1
通讯作者:
Ebrahimi, Mandana
Ebrahimi, Mandana
中科院分区:
医学4区
文献类型:
--
作者:
Mousavi, Seyed Mohsen;Montazeri, Ali;Ebrahimi, Mandana

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然而,乳腺癌是伊朗妇女最常见的恶性肿瘤之一;伊朗患者中乳腺癌的流行病学情况尚不确定。使用不同的搜索引擎对1998年1月至2005年12月发表的文章进行文献综述:MEDLINE,教育,文化和研究学术中心的科学信息数据库,以及94种波斯医学期刊的2000多期。将标题“Breast Cancer”、“Breast Tumor”、“Breast Cancer”和“Breast Cancer”与单词“Iran”组合进行检索。共审查了85篇全文。这些研究结果表明,参与者的年龄从15岁到84岁不等,其中40-49岁的人最多。妇女乳腺癌发病率为每100 000人中有22人。同一人群的患病率为每10万人120例。I期诊断为18%,II期为57%,III期为25%。约72%的患者被诊断为肿瘤超过2 cm。63%的患者在诊断时有淋巴结受累。浸润性导管癌最常见,占77%,小叶癌最少,占5%。这一审查表明,伊朗对乳腺癌的流行病学方面进行了比较充分的研究。其临床方面的研究是显而易见的,需要成为即将到来的调查的核心部分。
Breast cancer is one of the most frequent malignancies among Iranian women, however; the epidemiological aspects of breast cancer among Iranian patients are uncertain. A literature review of the published articles from January 1998 to December 2005 was conducted using different search engines: MEDLINE, Scientific information data base of Academic Center for Education, Culture and Research, and over 2000 issues of 94 Persian medical journals. The headings "Breast Cancer," "Breast Tumor," "Breast Malignancy," and "Breast Carcinoma" were combined with the word "Iran" to execute the search. In all, 85 full papers were reviewed. These findings showed that participants ranged from 15 to 84 years old, with those 40-49 being the most prevalent. The incidence of breast cancer in women was 22 per 100,000. The prevalence in this same population was 120 per 100,000. Stage I was diagnosed in 18%, stage II in 57% and stage III in 25% of the cases. About 72% of the patients were diagnosed with a tumor over 2 cm. Sixty-three percent of the patients had lymph node involvement at the diagnostic time. Infiltrative ductal carcinoma was found to be the most common at 77% and lobular carcinoma the least at 5%. This review indicates that the epidemiological aspects of breast cancer in Iran are relatively well-studied. Shortcomings in study of its clinical aspects are evident and need to be a central part of upcoming investigations.