Implementing personalized medicine in a cancer center.
Implementing personalized medicine in a cancer center.
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DOI：
10.1097/ppo.0b013e318238216e
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发表时间：
2011-11
期刊：
影响因子：
--
通讯作者：
Dalton WS
中科院分区：
文献类型：
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作者：
Fenstermacher DA;Wenham RM;Rollison DE;Dalton WS
2006年，莫菲特癌症中心与美国的患者、社区临床医生、工业界、学术界和17家医院合作，开始一项名为Total Cancer Care™的个性化癌症护理计划。Total Cancer Care旨在收集患者一生中的肿瘤标本和临床数据，目标是找到“在正确的时间为正确的患者提供正确的治疗”。由于全面癌症护理是与患者的合作伙伴关系，涉及收集临床数据和肿瘤标本用于研究目的，因此制定了正式的方案和患者同意程序，并构建了信息技术平台，为临床和分子分析数据提供了一个强大的“仓库”。到目前为止，来自Moffitt和联盟医疗中心的76，000多名癌症患者已参与该方案。TCC计划开发了许多能力和资源，为个性化医疗奠定了基础。
In 2006, the Moffitt Cancer Center partnered with patients, community clinicians, industry, academia, and seventeen hospitals in the United States to begin a personalized cancer care initiative called Total Cancer Care™ . Total Cancer Care was designed to collect tumor specimens and clinical data throughout a patient’s lifetime with the goal of finding “the right treatment, for the right patient, at the right time.” Because Total Cancer Care is a partnership with the patient and involves collection of clinical data and tumor specimens for research purposes, a formal protocol and patient consent process was developed and an information technology platform was constructed to provide a robust “warehouse” for clinical and molecular profiling data. To date, over 76,000 cancer patients from Moffitt and consortium medical centers have been enrolled in the protocol. The TCC initiative has developed many of the capabilities and resources that are building the foundation of personalized medicine.