Proteomics-informed physiologically-based pharmacokinetic (PBPK) modeling revealed differential effects of UGT2B17 variability on the pharmacokinetics of diclofenac following intravenous and oral administration.
Proteomics-informed physiologically-based pharmacokinetic (PBPK) modeling revealed differential effects of UGT2B17 variability on the pharmacokinetics of diclofenac following intravenous and oral administration.
复制标题
基于蛋白质组学的生理药代动力学 (PBPK) 模型揭示了 UGT2B17 变异性对静脉和口服给药后双氯芬酸药代动力学的不同影响。
DOI:
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发表时间:
2022
期刊:
影响因子:
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通讯作者:
Prasad,Bhagwat
中科院分区:
文献类型:
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作者:
Ahire,DeepakS;Prasad,Bhagwat