Social class in asthma and allergic rhinitis:: a national cohort study over three decades
Social class in asthma and allergic rhinitis:: a national cohort study over three decades
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DOI：
10.1183/09031936.05.00022105
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发表时间：
2005-12-01
影响因子：
24.3
通讯作者：
Rasmussen, F
中科院分区：
文献类型：
--
作者：
Bråbäck, L;Hjern, A;Rasmussen, F
这项研究的目的是评估过敏性鼻炎和哮喘与社会阶层的关系是否不同，以及这些关系是否随着时间的推移而改变。瑞典兵役征兵登记处与其他两个国家登记处联系在一起，共有1247人，对1952 ~ 1977年出生的10038名男性应征入伍者进行了调查，哮喘合并变应性鼻炎的比例为15%在最老的队列中，44%在最年轻的队列中。低社会经济地位（SES）与无过敏性鼻炎的哮喘风险增加（评估为比值比）相关（1.14，95%置信区间（CI）1.11-1.17），但与过敏性鼻炎的哮喘风险略有降低（0.96，95% CI 0.93-1.00）。过敏性鼻炎的风险为0.84，95% CI 0.82-0.85。SES和出生年份之间的积极互动发生在所有三个条件。在最早的队列中，低SES与哮喘伴变应性鼻炎的风险降低有关（0.72，95% CI 0.53-0.82），但在最近的队列中，风险略有增加（1.07，95% CI 1.01-1.14）。总之，社会阶层的作用随着时间的推移而改变。哮喘和过敏性鼻炎发病率上升最快的是社会经济地位较低的应征入伍者。
The aim of this study was to assess whether the association with social class differed between allergic rhinitis and asthma and whether these associations have changed over time.The Swedish Military Service Conscription Register was linked to two other national registers for 1,247,038 male conscripts in successive cohorts born between 1952 and 1977.The percentage of asthma cases associated with allergic rhinitis was 15% in the oldest cohort and 44% in the youngest cohort. Low socio-economic status (SES) was associated with an increased risk (assessed as odds ratio) of asthma without allergic rhinitis (1.14, 95% confidence interval (CI) 1.11-1.17) but a slightly reduced risk of asthma with allergic rhinitis (0.96, 95% CI 0.93-1.00). The risk of allergic rhinitis was 0.84, 95% CI 0.82-0.85. A positive interaction between SES and year of birth occurred in all three conditions. Low SES was related to a reduced risk of asthma with allergic rhinitis in the earliest cohort (0.72, 95% CI 0.53-0.82) but a slightly increased risk in the most recent cohort (1.07, 95% CI 1.01-1.14).In conclusion, the role of social class has changed over, time. The steepest increase in asthma and allergic rhinitis occurred in conscripts with a low socio-economic status.