Methods for Optimal Intervention in Gene Regulatory Networks.
Methods for Optimal Intervention in Gene Regulatory Networks.
复制标题
基因调控网络的最佳干预方法。
DOI：
10.1109/msp.2011.943128
复制
发表时间：
2012
影响因子：
14.9
通讯作者：
Schonfeld,Dan
中科院分区：
文献类型：
--
作者：
Bouaynaya,Nidhal;Shterenberg,Roman;Schonfeld,Dan
In this column, we review recent results in gene regulatory network modeling and discuss various control mechanisms used to modify their cellular dynamics. We subsequently describe a new intervention strategy based on optimal perturbations, which force the network to converge to a desired steady-state distribution of gene regulation.
