Lifetime anorexia nervosa in young men in the community: five cases and their co-twins.
Lifetime anorexia nervosa in young men in the community: five cases and their co-twins.
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社区年轻男性终生神经性厌食症：五例及其双胞胎。
DOI：
10.1002/eat.20525
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Kaprio,Jaakko
中科院分区：
文献类型：
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作者：
Raevuori,Anu;Keski-Rahkonen,Anna;Hoek,HansW;Sihvola,Elina;Rissanen,Aila;Kaprio,Jaakko
目的描述神经性厌食症(AN)在一般人群及其同卵双胞胎青年男性中的模式、共病和转归。方法对芬兰双胞胎队列中1975-1979年间出生的男性(N=2,122)进行终身饮食障碍的问卷调查。对于筛查阳性的DSM-IV结构化临床访谈的简短版本的管理导致了五名参与者的终生诊断，这里描述了他们的同卵双胞胎。结果在男性中，超重通常先于AN，身体变形障碍的症状，特别是肌肉变形障碍的症状，在厌食症不和谐的同卵双胞胎中很常见。在先证者及其同卵双胞胎中都存在情感性和焦虑性障碍。结论我们在普通人群中发现了AN、情感性和焦虑性障碍以及肌肉变形症状的强烈家族聚集性。在男性中，肌肉变形障碍可能代表了AN的另一种表型。©2008威利期刊公司Int J Eat Disord 2008
ObjectiveTo describe patterns, comorbidity, and outcomes from a case series of anorexia nervosa (AN) among young men from the general population and their co‐twins.MethodMen (N= 2,122) born between 1975 and 1979 from Finnish twin cohorts were screened for lifetime eating disorders by questionnaire. The administration of the short version of the Structured Clinical Interview for DSM‐IV for screen positives led to a lifetime AN diagnosis in five participants, described here with their co‐twins.ResultsIn males, overweight commonly predated AN, and symptoms of body dysmorphic disorder, particularly of muscle dysmorphia, were common among the anorexia‐discordant co‐twins. Affective and anxiety disorders were present in both the probands and their co‐twins.ConclusionWe found a strong familial clustering of AN, affective and anxiety disorders, and symptoms of muscle dysmorphia among men in the general population. In men, muscle dysmorphia may represent an alternative phenotype of AN. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2008