Smoking, quitting, and mortality in a Chinese cohort of retired men
Smoking, quitting, and mortality in a Chinese cohort of retired men
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DOI：
10.1016/s1047-2797(01)00258-7
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发表时间：
2002-07-01
影响因子：
5.6
通讯作者：
Li, LS
中科院分区：
文献类型：
--
作者：
Lam, TH;He, Y;Li, LS
目的：探讨吸烟、戒烟与老年男性死亡率的关系。设计与方法：采用队列分析方法，对西安市中国地区老年男性吸烟、戒烟与死亡率的关系进行研究。1987年对1268名60岁及以上的军队离退休男性干部进行了12年的跟踪调查。结果：基线调查中，388名男性从不吸烟，461名曾经吸烟，419名现在吸烟。截至1999年5月，共有299人死亡。调整年龄、血压、体重指数、总胆固醇、甘油三酯、饮酒、运动和既往疾病等因素后，吸烟、慢性阻塞性肺疾病(COPD)、肺癌和冠心病死亡的相对危险度[95%可信区间(CI)]分别为1.34(1.02~1.76)、3.23(0.95~10.91)、2.31(0.95~5.61)和1.60(0.81~3.19)。随着吸烟量和吸烟期的增加，患病风险显著增加。与现有吸烟者相比，既往吸烟者总死亡率(超额风险降低56%)和先期冠心病死亡的风险较低，但COPD死亡的风险较高。结论：吸烟是中国老年人的主要死亡原因，戒烟可以挽救生命。在控制日益增长的烟草流行中，应强调及早认识到COPD症状的重要性，然后迅速戒烟。《安妮·流行病学》2002；12：316-320。(C)2002 Elsevier Science Inc.保留所有权利。
PURPOSE: To examine the relationship between smoking, quitting, and mortality in older Chinese men.DESIGN AND METHODS: A cohort analytic study was carried out in Xi'an, China. A total of 1268 retired male military cadres aged 60 or older were examined in 1987 and followed for 12 years.RESULTS: At baseline, 388 men were never-smokers, 461 were former smokers, and 419 were current smokers. Through May 1999, a total of 299 had died. The relative risks [95% confidence intervals (CI)] for ever-smoking, after adjusting for age, blood pressure, body mass index, total cholesterol, triglycerides, alcohol drinking, exercise and existing diseases, for deaths resulting from all causes, chronic obstructive pulmonary disease (COPD), lung cancer, and coronary heart disease (CHD) were, respectively, 1.34 (1.02-1.76), 3.23 (0.95-10.91), 2.31 (0.95-5.61), and 1.60 (0.81-3.19). The risks increased significantly with increasing amount and duration of smoking. Compared with current smokers, former smokers had lower risks of total mortality (excess risk reduction of 56%) and front CHD death, but had higher risks for COPD death.CONCLUSIONS: Smoking is a major cause of death in older Chinese and quitting can save lives. Early recognition of the significance of COPD symptoms followed by prompt quitting should be emphasized in the control of the growing tobacco epidemic. Ann Epidemiol 2002; 12:316-320. (C) 2002 Elsevier Science Inc. All rights reserved.