Human cytomegalovirus DNA. I. Molecular weight and infectivity
Human cytomegalovirus DNA. I. Molecular weight and infectivity
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人类巨细胞病毒 DNA。
DOI：
10.1128/jvi.26.3.813-816.1978
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发表时间：
1978
影响因子：
5.4
通讯作者：
J. van der Noordaa
中科院分区：
文献类型：
--
作者：
J. Geelen;C. Walig;P. Wertheim;J. van der Noordaa
从纯化的病毒体中分离人巨细胞病毒DNA（AD 169株），并通过蔗糖密度梯度离心进一步纯化。通过电子显微镜研究病毒DNA分子，发现其为线性，长度为76.22 +/- 5.22 μ m，对应分子量为147 +/- 6.2 x 10（6）。当在人类胚胎肺细胞中测试时，DNA具有感染性。
Human cytomegalovirus DNA (strain AD 169) was isolated from purified virions and further purified by sucrose density gradient centrifugation. The viral DNA molecules were studied by electron microscopy and found to be linear and to have a length of 76.22 +/- 5.22 micron, corresponding to a molecular weight of 147 +/- 6.2 x 10(6). The DNA was infectious when tested in human embryonic lung cells.