Synthesis of Thermo-Sensitive Micellar Aggregates Self-Assembled from Biotinylated PNAS-b-PNIPAAm-b-PCL Triblock Copolymers for Tumor Targeting
Synthesis of Thermo-Sensitive Micellar Aggregates Self-Assembled from Biotinylated PNAS-b-PNIPAAm-b-PCL Triblock Copolymers for Tumor Targeting
复制标题
生物素化 PNAS-b-PNIPAAm-b-PCL 三嵌段共聚物自组装热敏胶束聚集体的合成用于肿瘤靶向
DOI：
10.1021/jp902637n
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发表时间：
2009-06
影响因子：
3.7
通讯作者：
D. Q. Wu
中科院分区：
文献类型：
--
作者：
S. X. Cheng;R. X. Zhuo;X. Z. Zhang;C. Y. Quan;C. Chang;G. B. Zhang;D. Q. Wu
采用可逆加成-断裂链转移（RAFT）聚合法合成了具有刺激敏感性的聚（N-丙烯酰氧基琥珀酰亚胺）-b-聚（N-异丙基丙烯酰胺）（PNAS-b-PNIPAAm）嵌段共聚物。通过使用二苯并噻吩的末端羧基，
The stimuli-sensitive diblock copolymer poly(N-acroyloxysuccinimide)-b-poly(N-isopropylacrylamide) (PNAS-b-PNIPAAm) was synthesized via reversible addition−fragmentation chain transfer (RAFT) polymerization. By using the terminal carboxyl group of the dib