Mind the gap: The role of time between sex with two consecutive partners on the transmission dynamics of gonorrhea
Mind the gap: The role of time between sex with two consecutive partners on the transmission dynamics of gonorrhea
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DOI：
10.1097/olq.0b013e3181612d33
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发表时间：
2008-05-01
影响因子：
3.1
通讯作者：
Edmunds, John
中科院分区：
文献类型：
--
作者：
Chen, Mark I.;Ghani, Azra C.;Edmunds, John
目的：性伴侣关系的持续时间和两个连续伴侣关系之间的时间（间隔长度）在人群之间存在差异。我们使用具有多个伙伴关系持续时间和间隙长度的数学模型来识别维持英国淋病传播的关系周期类型。研究设计：构建了淋病传播的数学模型，该模型跟踪伙伴关系的持续时间及其之前的间隙长度。全国性的性态度和生活方式的调查被用来parameterize模型人口到5个不同的伙伴关系长度（平均1天，2周，8周，30周，10年）和3个前间隙长度（14天，8周，1.5年）。淋病感染持续存在需要伴侣之间存在短间隔的个体的分类（喜欢）混合。患病率最高的是短（>1天-1个月），
Objective: Both the duration of sexual partnerships and the time between two consecutive partnerships (gap length) varies between populations. We use a mathematical model with multiple partnership durations and gap lengths to identify the types of relationship cycles that sustain gonorrhea transmission in the United Kingdom.Study Design: A mathematical model for gonorrhea transmission was constructed which tracks the duration of partnerships and their preceding gap lengths. The National Survey of Sexual Attitudes and Lifestyles was used to parameterize the model population into 5 different partnership lengths (mean of 1 day, 2 weeks, 8 weeks, 30 weeks, and 10 years) and 3 preceding gap lengths (14 days, 8 weeks, and 1.5 years).Results: The model was able to reproduce patterns of gonococcal infection in the United Kingdom. Assortative (like-with-like) mixing of individuals with short gaps between partnerships was required for gonorrhea infection to persist. Prevalence was highest in individuals with short (>1 day-1 month-