An empirical test of the Information, Motivation and Behavioral Skills model of antiretroviral therapy adherence
An empirical test of the Information, Motivation and Behavioral Skills model of antiretroviral therapy adherence
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DOI：
10.1080/09540120500038058
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发表时间：
2005-08-01
影响因子：
1.7
通讯作者：
Fisher, JD
中科院分区：
文献类型：
--
作者：
Amico, KR;Toro-Alfonso, J;Fisher, JD
几乎完美地坚持要求严格的抗逆转录病毒治疗（ART）现在被认为是艾滋病毒阳性患者实现其生命维持益处的关键。尽管不依从会带来可怕的后果，但大量患者并没有遵循他们的ART方案。虽然有许多因素影响依从性，但文献中主要是对其中一个或一小部分的研究。多变量的，基于理论的模型的坚持行为是极大的兴趣。目前的研究测试了一个这样的模型，ART依从性的信息、动机和行为技能（IMB）模型（Fisher等人，审查中）。在波多黎各接受抗逆转录病毒治疗的HIV阳性患者样本（N = 200）中提供了关于依从性相关信息、动机和行为技能以及依从性行为本身的数据。结构方程模型检验用于评估ART依从性的IMB模型的命题，为模型提出的要素与扩展以前的工作之间的相互关系提供了支持。未来的研究和干预发展的影响进行了讨论。
Nearly perfect adherence to demanding antiretroviral therapy ( ART) is now recognized as essential for HIV-positive patients to realize its life sustaining benefits. Despite the dire consequences of non-adherence, a large number of patients do not follow their ART regimen. While many factors influence adherence, the literature is dominated by studies on only one or a small set of them. Multivariate, theory-based models of adherence behavior are of great interest. The current study tested one such model, the Information, Motivation and Behavioral Skills (IMB) model of ART adherence ( Fisher et al., under review). A sample of HIV-positive patients on ART in clinical care in Puerto Rico (N = 200) provided data on adherence-related information, motivation and behavioral skills as well as adherence behavior per se. Structural equation model tests used to assess the propositions of the IMB model of ART adherence provided support for the interrelations between the elements proposed by the model and extended previous work. Implications for future research and intervention development are discussed.