Structure of (-)-neodysidenin from Dysidea herbacea.: Implications for biosynthesis of 5,5,5-trichloroleucine peptides
Structure of (-)-neodysidenin from Dysidea herbacea.: Implications for biosynthesis of 5,5,5-trichloroleucine peptides
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DOI：
10.1021/ol006326u
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发表时间：
2000-08-24
期刊：
影响因子：
5.2
通讯作者：
Molinski, TF
中科院分区：
文献类型：
--
作者：
MacMillan, JB;Trousdale, EK;Molinski, TF
[图表]Neodysidenin是从大堡礁收集的海洋海绵Dysidea herbacea（Keller 1889）中分离出来的。完整的配置是从一个组合的方法，包括毛细管电泳的马氏衍生物。Neodysidenin属于L-系列三氯亮氨酸肽，N-甲基噻唑基丙氨酸残基（13 R）的构型与dysidenin相反。
[GRAPHICS]Neodysidenin was isolated from the marine sponge Dysidea herbacea (Keller 1889) collected on the Great Barrier Reef. The complete configuration was obtained from a combination of methods, including capillary electrophoresis of Marfey's derivatives. Neodysidenin belongs to the L-series of trichloroleucine peptides, and the configuration of the N-methyl thiazolyl alanine residue (13R) is opposite to that of dysidenin.