Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors
Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors
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DOI：
10.1016/j.gie.2006.07.046
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发表时间：
2007-06-01
影响因子：
7.7
通讯作者：
Chayama, Kazuaki
中科院分区：
文献类型：
--
作者：
Hirata, Mayuko;Tanaka, Shinji;Chayama, Kazuaki
背景：窄带成像（Narrow band imaging， NBI）采用滤光片进行红-绿-蓝顺序照明，从而缩小了光谱透射率的带宽。目的：本研究旨在阐明NBI放大在评估结直肠肿瘤坑型诊断中的临床应用价值。设计：这是一项回顾性研究。背景：广岛大学医院内窥镜科。患者及主要观察指标：共对148例结直肠病变、16例增生、84例管状腺瘤、48例早期癌进行组织学检查和诊断。病灶平均大小为15.6±7.28 mm。先在无色镜的NBI放大镜下观察病变，再在标准放大镜下观察病变，并记录凹坑模式。将NBI放大结果与标准放大镜下的结果进行比较，以评估NBI放大对诊断结直肠肿瘤的临床价值。结果：两种诊断方法对II型的符合率为88%(14/16)，对III型的符合率为100%(2/2)，对III型的符合率为98%(73/75)，对IV型的符合率为88%(7/8)，对Vi型的符合率为78%(25/32)，对VN型凹坑型的符合率为100%（3/3）。在6%（1/16）的增生和99%（83/84）的管状腺瘤中，NBI显示基于表面毛细血管的褐色变化。这种颜色描绘的差异是显著的。局限性：本研究为单中心研究。结论：NBI放大镜对结直肠肿瘤的凹坑形态的判断与标准放大镜下的染色内镜几乎相同，而且在没有染色内镜的情况下，NBI可以区分肿瘤和非肿瘤病变。
Background: Narrow band imaging (NBI) uses optical filters for red-green-blue sequential illumination and narrows the bandwidth of spectral transmittance.Objective: This study aimed to clarify the clinical usefulness of NBI magnification in assessment of pit patterns for diagnosis of colorectal tumors.Design: This was a retrospective studySetting: Department of Endoscopy Hiroshima University Hospital.Patients and Main Outcome Measurements: A total of 148 colorectal lesions, 16 hyperplasias, 84 tubular adenomas, and 48 early carcinomas were examined and diagnosed histologically. Mean size of lesions was 15.6 +/- 7.28 mm. Lesions were observed first under NBI magnification without chromoencloscopy and then under standard magnification with chromoendoscopy, and pit patterns were recorded. Results of NBI magnification were compared with those of standard magnification with chromoendoscopy to assess the clinical usefulness of NBI magnification for diagnosing colorectal neoplasia.Results: Correspondence between the two diagnostic methods was 88% (14/16) for type II, 100% (2/2) for type IIIs, 98% (73/75) for type III,, 88% (7/8) for type IV, 78% (25/32) for type Vi, and 100% (3/3) for type VN pit patterns. NBI depicted brownish change on the basis of surface capillaries in 6% (1/16) of hyperplasia and 99% (83/84) of tubular adenomas. This difference in color depiction was significant.Limitations: This study was performed in single center.Conclusions: Determination of pit patterns of colorectal neoplasias by NBI magnification was nearly the same as that by standard magnification with chromoendoscopy Furthermore, NBI can distinguish neoplastic and nonneoplastic lesions without chromoendoscopy.