Preoperative CT texture analysis of gastric cancer: correlations with postoperative TNM staging
Preoperative CT texture analysis of gastric cancer: correlations with postoperative TNM staging
复制标题
胃癌术前CT纹理分析：与术后TNM分期的相关性
DOI：
10.1016/j.crad.2018.03.005
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发表时间：
2018-08-01
影响因子：
2.6
通讯作者：
Zhou, Z.
中科院分区：
文献类型：
--
作者：
Liu, S.;Shi, H.;Zhou, Z.
目的：为探讨CT纹理分析在胃癌病理分期预测中的作用，材料与方法：回顾性分析153例胃癌患者（男112例，女41例）术前增强CT图像。感兴趣区域（ROI）沿动脉和静脉CT图像上显示最大的部分上的病变边缘手动绘制沿着，产生纹理参数，包括平均值、最大频率、众数、偏度、峰度和熵。用斯皮尔曼相关性检验分析纹理参数与病理分期的相关性。结果：动脉期最大频率、静脉期平均频率、最大频率、众数与T分期、N分期、总体分期呈正相关（均P < 0. 05），静脉期平均频率、最大频率、众数与T分期、N分期、总体分期呈正相关（均P < 0. 05），动脉期平均频率、最大频率、众数与T分期、N分期、总体分期呈正相关（均P < 0. 05）。
AIM: To explore the role of computed tomography (CT) texture analysis in predicting pathologic stage of gastric cancers.MATERIALS AND METHODS: Preoperative enhanced CT images of 153 patients (112 men, 41 women) with gastric cancers were reviewed retrospectively. Regions of interest (ROIs) were manually drawn along the margin of the lesion on the section where it appeared largest on the arterial and venous CT images, which yielded texture parameters, including mean, maximum frequency, mode, skewness, kurtosis, and entropy. Correlations between texture parameters and pathological stage were analysed with Spearman's correlation test. The diagnostic performance of CT texture parameters in differentiating different stages was evaluated using receiver operating characteristic (ROC) analysis.RESULTS: Maximum frequency in the arterial phase and mean, maximum frequency, mode in the venous phase correlated positively with T stage, N stage, and overall stage (all p