Polychlorinated dibenzo-p-dioxins and dibenzofurans formed from sucralose at high temperatures
Polychlorinated dibenzo-p-dioxins and dibenzofurans formed from sucralose at high temperatures
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DOI：
10.1038/srep02946
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发表时间：
2013-10-15
影响因子：
4.6
通讯作者：
Zheng, Minghui
中科院分区：
文献类型：
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作者：
Dong, Shujun;Liu, Guorui;Zheng, Minghui
三氯蔗糖是一种广泛使用的人工高强度甜味剂。尽管一些研究人员对三氯蔗糖的安全性提出了质疑，但它仍然可以在全球范围内的各种食品和饮料中找到，包括烘焙食品。三氯蔗糖可能在高温下分解，并参与氯化反应，产生剧毒化合物。在这里，我们证明，在高温下加热三氯蔗糖在不锈钢或其他金属器皿中的存在下的锈（Al 2 O3，Fe 2 O3和CuO）产生多氯二苯并二恶英和二苯并呋喃（二恶英/呋喃）。在三氯蔗糖加热过程中产生的烟雾和加热后的残留物中发现了多氯二苯并对二恶英和多氯二苯并呋喃。CuO提高PCDD/F的产量相比，Al 2 O3和Fe 2 O3。
Sucralose is a widely-used artificial high-intensity sweetener. Although doubts have been raised about the safety of sucralose by several researchers, it can still be found in a broad range of foods and beverages worldwide, including in baked goods. Sucralose may decompose at high temperatures, and participate in chlorination reactions, generating highly toxic compounds. Here, we demonstrate that heating sucralose at high temperatures in stainless steel or other metal utensils in the presence of rust (Al2O3, Fe2O3, and CuO) produces polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). PCDD/Fs were found in smoke generated during the heating of sucralose and in the residues after heating. CuO enhanced the PCDD/F yield in comparison with Al2O3 and Fe2O3.