Object-location memory: A lesion-behavior mapping study in stroke patients
Object-location memory: A lesion-behavior mapping study in stroke patients
复制标题
物体位置记忆：中风患者的病变行为映射研究
DOI：
10.1016/j.bandc.2009.07.012
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发表时间：
2009
影响因子：
2.5
通讯作者：
A. Postma
中科院分区：
文献类型：
--
作者：
M. Asselen;Roy P.C. Kessels;Roy P.C. Kessels;C. Frijns;L. Kappelle;S. F. Neggers;A. Postma
物体位置记忆是空间记忆的一种重要形式，包括不同的子成分，每个子成分处理记忆中特定类型的信息，即记住物体，记住位置并将这些特征结合在记忆中。在目前的研究中，我们调查了绑定分类（相对）或坐标（确切）的位置信息与记忆中的对象的神经相关性。因此，使用了对象位置记忆电池，包括评估对象位置记忆的不同任务条件，即位置信息本身的记忆，以及将对象信息与坐标和分类位置信息绑定。对61例脑局灶性病变的脑卒中患者进行了检查，并与77例健康对照组进行了比较。采用病灶减影法确定重叠面积。结果表明，一个重要的作用，左后顶叶皮层在绑定的分类和坐标位置与对象信息。此外，海马体似乎对分类物体位置记忆很重要。这表明，分类和协调对象位置记忆依赖于类似的认知和神经系统。
Object-location memory is an important form of spatial memory, comprising different subcomponents that each process specific types of information within memory, i.e. remembering objects, remembering positions and binding these features in memory. In the current study we investigated the neural correlates of binding categorical (relative) or coordinate (exact) position information with objects in memory. Therefore, an object-location memory battery was used, including different task conditions assessing object-location memory, i.e. memory for position information per se, and binding object information with coordinate and categorical position information. Sixty-one stroke patients with focal brain lesions were examined and compared with 77 healthy matched controls. The lesion subtraction method was used to define the area of overlap. Results indicate an important role of the left posterior parietal cortex in the binding of both categorical and coordinate positions with object information. Additionally, the hippocampus seems important for categorical object-location memory. This suggests that categorical and coordinate object-location memory depend on similar cognitive and neural systems.