Written in Blood: Applying Shape Grammars to Retinal Vasculatures
Written in Blood: Applying Shape Grammars to Retinal Vasculatures
复制标题
用血写成：将形状语法应用于视网膜脉管系统
DOI：
10.1167/tvst.9.9.36
复制
发表时间：
2020
影响因子：
3
通讯作者：
Cagan, Jonathan
中科院分区：
文献类型：
--
作者：
Yeh, Ryan Y.;Nischal, Ken K.;LeDuc, Philip;Cagan, Jonathan
目的：视网膜内的血管网络对于维持组织灌注和良好视力至关重要。他们的复杂性和独特的模式往往需要一个陡峭的学习曲线，为人类确定的趋势和变化的形状和拓扑结构的网络，即使存在很多重要的信息，以确定疾病thems.Methods：通过图像处理，血管是孤立的眼底图像的其他功能，迫使观众专注于复杂的血管功能。本文探讨了一种方法，使用基于形状的语法来描述视网膜血管系统，并生成逼真的和越来越不现实的人工血管网络，然后由眼科医生通过数字调查进行审查。眼科医生被问到这些人造血管网络是否真实或不真实。结果：只有三个规则（初始，分支，和曲线），语法完成这些目标。通过向现有网络中存在的规则参数添加噪声来生成网络。通过对使用不同噪声参数生成的合成网络的调查，揭示了分支规则中的噪声与现实关联之间的相关性。通过创建一种语言来描述视网膜血管系统，本文允许对视网膜的这种重要但不太了解的特征进行新的洞察，其在未来可能在诊断或帮助预测眼部疾病类型中发挥作用。翻译相关性：应用形状语法来描述视网膜血管允许新的理解，这反过来又提供了新的诊断工具的潜力。
Purpose: Blood vessel networks within the retina are crucial for maintaining tissue perfusion and therefore good vision. Their complexity and unique patterns often require a steep learning curve for humans to identify trends and changes in the shape and topology of the networks, even though there exists much information important to identifying disease within them.Methods: Through image processing, the vasculature is isolated from other features of the fundus images, forcing the viewer to focus on the complex vascular feature. This article explores an approach using a grammar based on shape to describe retinal vasculature and to generate realistic and increasingly unrealistic artificial vascular networks that are then reviewed by ophthalmologists via digital survey. The ophthalmologists are asked whether these artificial vascular networks appeared realistic or unrealistic.Results: With only three rules (initiate, branch, and curve), the grammar accomplishes these goals. Networks are generated by adding noise to rule parameters present in existing networks. Via the survey of synthetic networks generated with different noise parameters, a correlation between noise in the branch rule and realistic association is revealed.Conclusions: By creating a language to describe retinal vasculature, this article allows for the potential of new insight into such an important but less understood feature of the retina, which in the future may play a role in diagnosing or helping to predict types of ocular disease.Translational Relevance: Applying shape grammar to describe retinal vasculature permits new understanding, which in turn provides the potential for new diagnostic tools.
登录
查看更多内容
DOI：
10.1109/mvhi.2010.182
发表时间：
2010
期刊：
2010 International Conference on Machine Vision and Human-machine Interface
影响因子：
--
作者：
Xuemei Liu;Huan Liu;A. Hao;Qinping Zhao
通讯作者：
Qinping Zhao
DOI：
10.15676/ijeei.2015.7.4.14
发表时间：
2016
期刊：
2010 International Conference on Machine Vision and Human-machine Interface
影响因子：
--
作者：
G. Hichem;Fraj Chouchene;H. Belmabrouk
通讯作者：
H. Belmabrouk
影响因子：
120.7
作者：
Gulshan, Varun;Peng, Lily;Webster, R.
通讯作者：
Webster, R.
影响因子：
5
作者：
Bhaskaranand, Malavika;Ramachandra, Chaithanya;Solanki, Kaushal
通讯作者：
Solanki, Kaushal