Three-Dimensional Printing (3DP) of neonatal head phantom for ultrasound: Thermocouple embedding and simulation of bone
Three-Dimensional Printing (3DP) of neonatal head phantom for ultrasound: Thermocouple embedding and simulation of bone
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DOI：
10.1016/j.medengphy.2011.10.012
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发表时间：
2012-09-01
影响因子：
2.2
通讯作者：
Harris, Russell A.
中科院分区：
文献类型：
--
作者：
Gatto, Matteo;Memoli, Gianluca;Harris, Russell A.
设计并制造了一种新生儿头部模型，该模型由椭圆形几何形状组成，并包括用于模拟囟门的圆形孔径，以允许对早产儿经颅超声扫描期间组织中的温升进行客观评估。在有限元分析的基础上确定了一系列热电偶的精确位置，该分析确定了体模几何结构内热监测的关键目标点。三维打印（3DP）用于制造颅骨体模，随后填充专用的大脑模拟材料。发现一种新型3DP材料组合能够模拟新生儿颅骨的声学特性。类似地，研究人员对组织模拟物的标准配方进行了研究，直到发现一种可以模拟婴儿的大脑。在制造过程中，成功采用了一种特定策略，将热电偶嵌入3DP颅骨体模中。使用过程中机器视觉系统来评估制造的颅骨体模内沉积的热电偶的正确位置。外部硅胶制成的皮肤样覆盖物完成了体模，并通过直接快速模具（DRT）技术制造。(C)2011年IPEM。由爱思唯尔有限公司出版。保留所有权利。
A neonatal head phantom, comprising of an ellipsoidal geometry and including a circular aperture for simulating the fontanel was designed and fabricated, in order to allow an objective assessment of thermal rise in tissues during trans-cranial ultrasonic scanning of pre-term neonates. The precise position of a series of thermocouples was determined on the basis of finite-element analysis, which identified crucial target points for the thermal monitoring within the phantom geometry. Three-Dimensional Printing (3DP) was employed for the manufacture of the skull phantom, which was subsequently filled with dedicated brain-mimic material. A novel 3DP material combination was found to be able to mimic the acoustic properties of neonatal skull bone. Similarly, variations of a standard recipe for tissue mimic were examined, until one was found to mimic the brain of an infant. A specific strategy was successfully pursued to embed a thermocouple within the 3DP skull phantom during the manufacturing process. An in-process machine vision system was used to assess the correct position of the deposited thermocouple inside the fabricated skull phantom. An external silicone-made skin-like covering completed the phantom and was manufactured through a Direct Rapid Tooling (DRT) technique. (C) 2011 IPEM. Published by Elsevier Ltd. All rights reserved.