TUMESCENT TECHNIQUE FOR LOCAL-ANESTHESIA IMPROVES SAFETY IN LARGE-VOLUME LIPOSUCTION
TUMESCENT TECHNIQUE FOR LOCAL-ANESTHESIA IMPROVES SAFETY IN LARGE-VOLUME LIPOSUCTION
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DOI：
10.1097/00006534-199311000-00014
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发表时间：
1993-11-01
影响因子：
3.6
通讯作者：
KLEIN, JA
中科院分区：
文献类型：
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作者：
KLEIN, JA
局部麻醉肿胀技术通过几乎消除手术失血和完全消除全身麻醉的风险，提高了大容量吸脂术（大于或等于1500 ml脂肪）的安全性。本文报告了两项应用肿胀法进行大容量吸脂术的前瞻性研究结果，共112例，平均利多卡因用量为33.3mg/kg，平均吸出物量为2657 ml，平均吸出脂肪量为1945 ml。吸脂术平均抽取全血18.5ml。每去除1000 ml脂肪，抽取9.7 ml全血。在1991年治疗的31例大容量吸脂患者中，术前和术后1周的血细胞比容平均差异为-1.9%。在第二项研究中，一名体重75 kg的妇女接受了35 mg/kg利多卡因两次单独给药，第一次不吸脂，25天后吸脂;血浆利多卡因浓度峰值出现在开始浸润后14和11小时，分别为2.37和1.86 μ g/ml。
The tumescent technique for local anesthesia improves the safety of large-volume liposuction (greater-than-or-equal-to 1500 ml of fat) by virtually eliminating surgical blood loss and by completely eliminating the risks of general anesthesia. Results of two prospective studies of large-volume liposuction using the tumescent technique are reported.In 112 patients, the mean lidocaine dosage was 33.3 mg/kg, the mean volume of aspirated material was 2657 ml, and the mean volume of supranatant fat was 1945 ml. The mean volume of whole blood aspirated by liposuction was 18.5 ml. For each 1000 ml of fat removed, 9.7 ml of whole blood was suctioned. In 31 large-volume liposuction patients treated in 1991, the mean difference between preoperative and 1-week postoperative hematocrits was -1.9 percent. The last 87 patients received no parenteral sedation.In a second study, a 75-kg woman received 35 mg/kg of lidocaine on two separate occasions, first without liposuction and 25 days later with liposuction; peak plasma lidocaine concentrations occurred at 14 and 11 hours after beginning the infiltration and were 2.37 and 1.86 mug/ml, respectively.