Deficiencia de zinc y sus implicaciones funcionales

Deficiencia de zinc y sus implicaciones funcionales
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DOI:
10.1590/s0036-36341998000200010
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发表时间:
1998-03
影响因子:
2.3
通讯作者:
J. Rosado
J. Rosado
中科院分区:
医学4区
文献类型:
--
作者:
J. Rosado

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本文的目的是回顾理论方面和研究在墨西哥进行的建议存在边际缺锌的农村儿童及其对健康的后果。锌是人类不可或缺的营养素,因为它在几种代谢途径中起着重要作用:它作为生物膜的结构离子参与几种酶的催化位点,并与蛋白质合成密切相关。因此,它与功能和健康障碍有关,特别是在儿童中。墨西哥儿童锌的边际缺乏是相关的,因为它的潜在影响。研究表明,边际锌缺乏与基于富含锌吸收抑制剂的植物性食物的饮食有关。这种饮食习惯在农村地区和城市的贫困地区消费。边际锌缺乏被发现会导致感染性疾病的增加,特别是腹泻,以及认知功能的损害。
The purpose of this article is to review theoretical aspects and research performed in Mexico suggesting the existence of marginal zinc deficiency in rural children and its consequences on health. Zinc is an indispensable nutrient for humans since it plays an important role in several metabolic pathways: it participates in the catalytic site of several enzymes, as a structural ion of biological membranes and is closely associated to protein synthesis, among other functions. It is therefore related to functional and health impairments, specially in children. A marginal deficiency of zinc in Mexican children is relevant because of its potential effects. Studies suggest that marginal zinc deficiency is associated to diets based on plant foods wich are rich in zinc absorption inhibitors. Such diets are habitually consumed in rural areas and in poors areas of the cities. Marginal zinc deficiency was found to cause an increase in infectious diseases, specially diarrhea, and an impairment of the cognitive functions.