Larvicidal activity of lignans identified in Phryma leptostachya var. asiatica roots against three mosquito species
Larvicidal activity of lignans identified in Phryma leptostachya var. asiatica roots against three mosquito species
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DOI：
10.1021/jf048208h
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发表时间：
2005-02-23
影响因子：
6.1
通讯作者：
Ahn, YJ
中科院分区：
文献类型：
--
作者：
Park, IK;Shin, SC;Ahn, YJ
The insecticidal activity of phytochemicals isolated from the roots of Phryma leptostachya var. asiatica against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi was examined. The two constituents of P. leptostachya var. asiatica roots were identified as the leptostachyol acetate (1) and 8 -acetoxy-2,2',6-trimethoxy-3,4,4',5'-dimethylenedioxyphenyl-7,7'-dioxabicyclo-[3.3.0]octane (11) by spectroscopic analysis. Compound I was lethal to C. pipiens pallens, A. aegypti, and O. togoi at 10 ppm. Compound 11 showed weak or no insecticidal activity against three mosquito species at 10 ppm. The LC50 values of I against C. pipiens pallens, A. aegypti, and O. togoi were 0.41, 2.1, and 2.3 ppm, respectively. Naturally occurring P. leptostachya var. asiatica root-derived compounds merit further study as potential mosquito larval control agents or lead compounds.
