Visual metacontrast masking in migraine
Visual metacontrast masking in migraine
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DOI：
10.1177/0333102410380755
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发表时间：
2011-02-01
期刊：
影响因子：
4.9
通讯作者：
Tibber, Marc S.
中科院分区：
文献类型：
--
作者：
Shepherd, Alex J.;Wyatt, Geddes;Tibber, Marc S.
背景：在视觉元对比掩蔽中，如果在一个简短的目标刺激之前（前向掩蔽）或之后（后向掩蔽）有一个不重叠的掩蔽，那么它的可见性会大大降低。这些影响归因于视觉系统内的抑制过程。先前的两项研究使用了元对比掩蔽来评估偏头痛组和对照组的抑制功能，然而，每项研究都使用了不同类型的掩蔽，得到了不同的结果。受试者和方法：比较偏头痛组（有先兆者15例，无先兆者15例）和对照组（n = 15）的前向、后向及前后向联合掩蔽。基线试验也包括在内（仅限目标）。结果：对于所有类型的掩蔽，两个偏头痛组都比对照组更准确。然而，当掩蔽试验的表现相对于基线表示时，没有显着的组差异。然而，在某些条件下的表现与偏头痛的频率和最近一次发作的时间显著相关。结论：在这项研究中所采用的掩蔽任务的抑制过程似乎不会在偏头痛中受损。他们更好的整体表现可能反映了灵敏度的差异，这可能是随着偏头痛周期而变化的神经反应增强的结果。
Background: In visual metacontrast masking, the visibility of a brief target stimulus can be reduced substantially if it is preceded (forward masking) or followed (backward masking) by a non-overlapping mask. These effects have been attributed to inhibitory processes within the visual system. Two previous studies have used metacontrast masking to assess inhibitory function in migraine and control groups, however, each used different types of masking and obtained different results.Subjects and Methods: Forward, backward and combined forward and backward masking were compared in migraine (15 with visual aura, 15 without) and control (n = 15) groups. Baseline trials were also included (target only).Results: For all types of masking, both migraine groups were more accurate than the control group. When performance for the masking trials was expressed relative to baseline, however, there were no significant group differences. Performance in certain conditions nevertheless correlated significantly with migraine frequency and with the recency of the last attack.Conclusions: The inhibitory processes involved in the masking tasks employed in this study do not appear to be impaired in migraine. Their better overall performance may reflect a sensitivity difference, perhaps as a consequence of a heightened neuronal response, which varies with the migraine cycle.