Biocuration of functional annotation at the European nucleotide archive.
Biocuration of functional annotation at the European nucleotide archive.
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DOI：
10.1093/nar/gkv1311
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发表时间：
2016-01-04
影响因子：
14.9
通讯作者：
Cochrane G
中科院分区：
文献类型：
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作者：
Gibson R;Alako B;Amid C;Cerdeño-Tárraga A;Cleland I;Goodgame N;Ten Hoopen P;Jayathilaka S;Kay S;Leinonen R;Liu X;Pallreddy S;Pakseresht N;Rajan J;Rosselló M;Silvester N;Smirnov D;Toribio AL;Vaughan D;Zalunin V;Cochrane G
欧洲核苷酸档案（ENA; http：//www.ebi.ac.uk/ena）是一个用于提交、维护和展示核苷酸序列数据以及相关样品和实验信息的储存库。在这篇文章中，我们报告了2015年ENA的一般活动，显著的已发布数据集和主要成就。其次是关注功能注释的可持续生物定位，这是一个特别感受到测序增长压力的领域。功能注释的重要性，如何提交以及在数据量不断增加的背景下生物制造商的角色转变都进行了讨论。
The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data sets and major achievements. This is followed by a focus on sustainable biocuration of functional annotation, an area which has particularly felt the pressure of sequencing growth. The importance of functional annotation, how it can be submitted and the shifting role of the biocurator in the context of increasing volumes of data are all discussed.