Biomedical applications of thermally activated shape memory polymers.
Biomedical applications of thermally activated shape memory polymers.
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DOI：
10.1039/b923717h
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发表时间：
2010-05-14
影响因子：
--
通讯作者：
Maitland DJ
中科院分区：
文献类型：
--
作者：
Small W 4th;Singhal P;Wilson TS;Maitland DJ
形状记忆聚合物（SMP）是一种智能材料，可以记住主要形状，并且在给予适当的刺激时可以从变形的次要形状恢复到该主要形状。这种特性使它们能够通过微创手术以紧凑的形式输送到人体，并部署以实现复杂的最终形状。在这里，我们回顾了 SMP 的各种生物医学应用以及它们在驱动和生物相容性方面面临的挑战。虽然形状记忆行为已在热、光和化学环境中得到证实，但这里我们重点讨论热刺激的形状记忆聚合物。
Shape memory polymers (SMPs) are smart materials that can remember a primary shape and can return to this primary shape from a deformed secondary shape when given an appropriate stimulus. This property allows them to be delivered in a compact form via minimally invasive surgeries in humans, and deployed to achieve complex final shapes. Here we review the various biomedical applications of SMPs and the challenges they face with respect to actuation and biocompatibility. While shape memory behavior has been demonstrated with heat, light and chemical environment, here we focus our discussion on thermally stimulated SMPs.