Intercellular migration of centrioles in the germarium of Drosophila melanogaster. An electron microscopic study.
Intercellular migration of centrioles in the germarium of Drosophila melanogaster. An electron microscopic study.
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DOI：
10.1083/jcb.45.2.306
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发表时间：
1970-05
期刊：
影响因子：
--
通讯作者：
Strassheim JM
中科院分区：
文献类型：
--
作者：
Mahowald AP;Strassheim JM
在果蝇早期卵母细胞中发现了一簇中心粒。由于卵母细胞通过细胞间桥或环形管道系统连接到15个保育细胞，因此在电子显微镜的连续切片中分析了中心粒从保育细胞到卵母细胞的细胞间迁移在生殖器中出现中心粒簇的可能性。最初，未来卵室的所有16个细胞都具有中心粒，它们位于非核位置。当16个细胞的细胞团在生殖区的侧面排列成透镜状时，中心粒失去了它们的非核位置并向卵母细胞移动。当16个细胞的细胞簇被卵泡细胞包围时（第1阶段），在卵母细胞中发现14至17个中心粒。后来，这些中心粒位于卵母细胞核和卵泡细胞边界之间，并聚集成一个最大尺寸小于1.5 µ的簇。这些中心粒在卵母细胞中的命运尚不清楚。本文还描述了生殖器和早期卵母细胞的精细结构。
A cluster of centrioles has been found in the early Drosophila oocyte. Since the oocyte is connected to 15 nurse cells by a system of intercellular bridges or ring canals, the possibility that the cluster of centrioles arose in the germarium from an intercellular migration of centrioles from the nurse cells to the oocyte was analyzed in serial sections for the electron microscope. Initially, all of the 16 cells of the future egg chambers possess centrioles, which are located in a juxtanuclear position. At the time the 16 cell cluster becomes arranged in a lens-shaped layer laterally across the germarium, the centrioles lose their juxtanuclear position and move towards the oocyte. By the time the 16 cell cluster of cells is surrounded by follicle cells (Stage 1), between 14 and 17 centrioles are found in the oocyte. Later, these centrioles become located between the oocyte nucleus and the follicle cell border and become aggregated into a cluster less than 1.5 µ in its largest dimension. The fate of these centrioles in the oocyte is not known. The fine structure of the germarium and the early oocyte is also described.