A planar microfabricated fluid

A planar microfabricated fluid
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DOI:
10.1016/s0924-4247(97)80042-8
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发表时间:
1996-06-01
影响因子:
4.6
通讯作者:
Yager, P
Yager, P
中科院分区:
工程技术3区
文献类型:
--
作者:
Brody, JP;Osborn, TD;Yager, P

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许多血液测试必须在没有细胞物质存在的血浆上进行。在标准的实验室方案中,通过离心法获得纯净的血浆。为了制造小型化的血液传感器,需要一种不同于离心法的分离血浆的方法。我们描述了流体过滤器的设计、制造和测试,以满足这一需求,并具有一些普遍感兴趣的特性。特定设备的结果表明,我们可以很容易地从流体中去除直径为16微米的球体。这种过滤器可以重复使用,可以潜在地去除小至0.1微米的颗粒,并且易于制造。
Many blood tests must be performed on plasma without cellular matter present. Ln the standard laboratory protocol, pure plasma is obtained through centrifugation. in order to produce a miniaturized blood sensor, a method to separate plasma other than centrifugation is needed. We describe the design, fabrication, and testing of a fluid filter that fulfils this need, and also has some features of general interest. Results from a particular device show that we can easily remove 16 mu m diameter spheres from the fluid. This filter can be reusable, can potentially remove particles as small as 0.1 mu m, and is easily fabricated.